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DNase I–hypersensitive sites enhance α1(I) collagen gene expression in hepatic stellate cells

✍ Scribed by Yutaka Yata; Andrew Scanga; Andrea Gillan; Liu Yang; Shimon Reif; Michael Breindl; David A. Brenner; Richard A. Rippe

Book ID
111722129
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
556 KB
Volume
37
Category
Article
ISSN
0270-9139

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## Abstract Leptin is a 16‐kDa hormone with an array of biologic actions. We, and others, have demonstrated that leptin is critical to the development of liver fibrogenesis both in vitro and in the lean littermates of __ob__/__ob__ mice exposed to carbon tetrachloride (CCl~4~). Controversy exists a