𝔖 Bobbio Scriptorium
✦   LIBER   ✦

DNA vaccines: Successes and limitations in cancer and infectious disease

✍ Scribed by Devin B. Lowe; Michael H. Shearer; Ronald C. Kennedy

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
94 KB
Volume
98
Category
Article
ISSN
0730-2312

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Vaccination with plasmid DNA is an active area of investigation that is being applied to diseases including cancer and microbial pathogens associated with infectious diseases. Since its discovery, great progress has been made with the administration of DNA vaccines to initiate specific and effective immune responses against targeted illnesses. However, many obstacles still face its use in prophylactic and therapeutic vaccination scenarios. The nature of these difficulties alongside the successes and future of plasmid DNA will be discussed. J. Cell. Biochem. 98: 235–242, 2006. Β© 2006 Wiley‐Liss, Inc.

πŸ“œ SIMILAR VOLUMES

Scaling properties of childhood infectio
Scaling properties of childhood infectious diseases epidemics before and after mass vaccination in Canada
✍ Helen Trottier; Pierre Philippe πŸ“‚ Article πŸ“… 2005 πŸ› Elsevier Science 🌐 English βš– 301 KB

The goal of this paper is to analyse the scaling properties of childhood infectious disease time-series data. We present a scaling analysis of the distribution of epidemic sizes of measles, rubella, pertussis, and mumps outbreaks in Canada. This application provides a new approach in assessing infec

Protease-mediated arsenic prodrug strate
Protease-mediated arsenic prodrug strategy in cancer and infectious diseases: A hypothesis for targeted activation
✍ Emanuele Bellacchio; Marco G. Paggi πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 214 KB

## Abstract A strategy for the selective in vivo activation of prodrugs by proteases is presented. The approach is based on the design of polythiol peptides able to neutralize the toxicity of As(III) through chelation, and contemporarily to be recognized as substrates of a disease‐linked specific p