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DNA vaccines against malaria: Immunogenicity and protection in a rodent model

✍ Scribed by Malcolm J. Gardner; Denise L. Doolan; Richard C. Hedstrom; Ruobing Wang; Martha Sedegah; Robert A. Gramzinski; Joao C. AGUIAR; Helen Wang; Michal Margalith; Peter Hobart; Stephen L. Hoffman

Book ID: 109388599
Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 109 KB
Volume: 85
Category: Article
ISSN: 0022-3549
DOI: 10.1021/js960147h

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## Abstract Scaling up experimental protocols from rodents to humans is often not a straightforward procedure, and this particularly applies to cancer vaccines, where vaccination technology must be especially effective to overcome a variety of immune suppressive mechanisms. DNA electroporation (DNA