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DNA vaccination against neu reduces breast cancer incidence and metastasis in mice

✍ Scribed by Lachman, Lawrence B; Rao, Xiao-Mei; Kremer, Ronald H; Ozpolat, Bulent; Kiriakova, Galina; Price, Janet E


Book ID
110017798
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
274 KB
Volume
8
Category
Article
ISSN
0929-1903

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## Abstract Here, we describe the enhanced benefits of treating a highly aggressive breast cancer in mice with a combination of paclitaxel and immunization with a unique DNA‐based cell vaccine. An adenocarcinoma was isolated from a spontaneous neoplasm that arose in the mammary gland of a C3H/He mo