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DNA Transposition by the RAG1 and RAG2 Proteins: A Possible Source of Oncogenic Translocations

โœ Scribed by Kevin Hiom; Meni Melek; Martin Gellert

Book ID
117268348
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
215 KB
Volume
94
Category
Article
ISSN
0092-8674

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## Abstract In this paper we report the structural basis for the nonexpression of G1m(3) and Km(1, 2) allotypes in an IgG1 (__K__) human myeloma protein (protein LEC). Heavy and light chains spontaneously dissociate in sodium dodecyl sulfate polyacrylamide gels. Light chains appear to be covalently