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DNA topoisomerase IIβ (topo IIβ) activates a subset of neuronal genes

✍ Scribed by Kuniaki Sano; Mary Miyaji-Yamaguchi; Kimiko Tsutsui; Ken Tsutsui


Book ID
116776762
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
85 KB
Volume
65
Category
Article
ISSN
0168-0102

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Type II DNA topoisomerase activity is required to change DNA topology. It is important in the relaxation of DNA supercoils generated by cellular processes, such as transcription and replication, and it is essential for the condensation of chromosomes and their segregation during mitosis. In mammals