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DNA topoisomerase II inhibitors: new approaches to antitumour therapy


Book ID
120863620
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2002
Weight
139 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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Leukemias related to treatment with DNA
✍ Felix, Carolyn A. πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 127 KB

## Abstract The epipodophyllotoxins etoposide and teniposide and other DNA topoisomerase II inhibitors including anthracyclines and dactinomycin are highly efficacious anticancer drugs. All are associated with a distinct form of leukemia characterized by chromosomal translocations as a treatment co