DNA-targeting molecules as therapeutic agents

✍ Scribed by Waring, Michael J. editor

Publisher: Royal Society of Chemistry
Year: 2018
Tongue: English
Leaves: 432
Series: Chemical biology series 7
Category: Library

No coin nor oath required. For personal study only.

✦ Table of Contents

Content: DNA Recognition by Parallel Triplex Formation
Interfacial Inhibitors
Slow DNA Binding
Thermal Denaturation of Drug-DNA Complexes
Computer Simulations of Drug-DNA Interactions: A Personal Journey
Binding of Small Molecules to Trinucleotide DNA Repeats Associated with Neurodegenerative Diseases
Parsing the Enthalpy-Entropy Compensation Phenomenon of General DNA-Ligand Interactions by a `Gradient Determinant' Approach
Structural Studies of DNA-binding Metal Complexes of Therapeutic Importance
Therapeutic Potential of DNA Gene Targeting using Peptide Nucleic Acid (PNA)
Sequence-selective Interactions of Actinomycin D with DNA: Discovery of a Thermodynamic Switch
Molecular Modelling Approaches for Assessing Quadruplex-Small Molecule Interactions
Molecular Recognition of DNA by Py-Im Polyamides: From Discovery to Oncology
Synthetic Peptides for DNA Recognition Inspired by Transcription Factors
Targeting DNA Mismatches with Coordination Complexes
CRISPR Highlights and Transition of Cas9 into a Genome Editing Tool

✦ Subjects

Gene therapy;DNA-drug interactions;MEDICAL / Pharmacology;Genetic Therapy;DNA / drug effects

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