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DNA strand breaks and ADP-ribosyl transferase activation during cell differentiation

✍ Scribed by Farzaneh, Farzin; Zalin, Rosalind; Brill, David; Shall, Sydney

Book ID
109728234
Publisher
Nature Publishing Group
Year
1982
Tongue
English
Weight
625 KB
Volume
300
Category
Article
ISSN
0028-0836

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## Abstract We evaluated cell survival, DNA double strand breaks (dsbs), and DNA synthesis following camptothecin (CPT) alone or concurrent CPT and X‐radiation treatments in exponential‐phase cultures of a radioresistant human melanoma cell line. Cell survival was measured by a clonogenic assay. DN