DNA stemline heterogeneity of non-small cell lung carcinomas and differences in DNA ploidy between carcinomas and metastatic nodes
β Scribed by Ayabe, Hiroyoshi; Tomita, Masao; Kawahara, Katunobu; Tagawa, Yutaka; Tsuji, Hiroharu; Akamine, Shinji
- Book ID
- 122571573
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 511 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0169-5002
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A study of 187 surgical specimens of tumors of patients with non-small-cell lung carcinomas was carried out by means of flow cyto- metry. Eighty-four percent of the tumors were classified as tumors with abnormal DNA stemlines (DNA aneuploidy). Patients with tumors demonstrating DNA aneuploidy had si
In a cooperative study, 240 surgical specimens of patients with non-small cell lung carcinomas (NSCLC) were investigated by means of flow cytometry, xenotransplantation to athymic mice and, an in vitro short-term test for predicting resistance. Aneuploidy was found in 83% of the tumors, and 20% show