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DNA sequence analysis of the conserved region around the SOD1 gene locus in recessively inherited ALS

✍ Scribed by Wendy J. Broom; Daniel V. Johnson; Manuel Garber; Peter M. Andersen; Niall Lennon; John Landers; Chad Nusbaum; Carsten Russ; Robert H. Brown Jr.


Book ID
116771567
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
223 KB
Volume
463
Category
Article
ISSN
0304-3940

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A frequent TG deletion near the polyaden
✍ FE Kleiman; A. Oller RamΓ­rez; B Akerman; R Dodelson de Kremer; RA Gravel; CE Arg πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 363 KB πŸ‘ 2 views

While screening for new mutations in the HEXB gene, which encodes the beta-subunit of beta-hexosaminidase, a TG deletion (deltaTG) was found in the 3' untranslated region (3'UTR) of the gene, 7 bp upstream from the polyadenylation signal. Examination of DNA samples of 145 unrelated Argentinean indiv