DNA, RNA and hemoglobin cytophotometry of maturing erythroid cells from liver nodules in rauscher virus infected mice
✍ Scribed by Pär Sundelin; Lawrence R. Adams
- Publisher
- John Wiley and Sons
- Year
- 1967
- Tongue
- French
- Weight
- 503 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
✦ Synopsis
Cytophotometrically estimated cellular amounts of D N A , R N A and hemoglobin were compared in erythroid cells from liver nodules of Rauscher virus infected mice and from bone marrow of mice made anemic with phenylhydrazine. Atypical erythroblastoid cells with small amounts of hemoglobin from Rauscher virus infected animals had greater amounts of R N A per cell than cells with similar amouiits of hemoglobin from phenylhydrazine treated mice. Heavily hemoglobinized cells from virus treated animals tended to have postmitotic amounts of DNA, less cellular R N A and poorer correlation between cellular amounts of R N A and hemoglobin, than phenylhydrazine stimulated bone marrow cells. The cytochemical data support the concept that some Rauscher leukemia cells may contain small amounts of hemoglobin and have a certain capacity for maturation.