Control of DNA replication licensing in
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Hideo Nishitani; Zoi Lygerou
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Article
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2002
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John Wiley and Sons
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English
β 223 KB
To maintain genome integrity in eukaryotes, DNA must be duplicated precisely once before cell division occurs. A process called replication licensing ensures that chromosomes are replicated only once per cell cycle. Its control has been uncovered by the discovery of the CDKs (cyclin dependent kinase