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DNA polymorphisms at the lipoprotein lipase gene: associations in normal and hypertriglyceridaemic subjects

✍ Scribed by J.C. Chamberlain; J.A. Thorn; K. Oka; D.J. Galton; J. Stocks

Book ID
118896171
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
612 KB
Volume
79
Category
Article
ISSN
0021-9150

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Lipoprotein lipase (LPL) plays a central role in the metabolism of lipoproteins by hydrolyzing the core triglycerides of circulating very low density lipoproteins and chylomicrons. The enzyme is encoded by a gene about 30kb in size located on the short arm of human chromosome 8. We have determined t