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DNA mismatch repair and the transition to hormone independence in breast and prostate cancer

✍ Scribed by Lynn Martin; Mary Coffey; Mark Lawler; Donal Hollywood; Laure Marignol

Book ID: 116335371
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 404 KB
Volume: 291
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2009.10.007

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## Abstract Despite earlier detection and recent advances in surgery and radiation, prostate cancer is second only to lung cancer in male cancer deaths in the United States. Hormone therapy in the form of medical or surgical castration remains the mainstay of systemic treatment in prostate cancer.