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DNA mismatch repair and the significance of a sebaceous skin tumor for visceral cancer prevention

โœ Scribed by Roland Kruse; Thomas Ruzicka


Book ID
116757826
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
438 KB
Volume
10
Category
Article
ISSN
1471-4914

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Fourteen Italian families affected with hereditary nonpolyposis colorectal cancer (HNPCC) were screened for germline mutations at three DNA mismatch repair (MMR) genes, MSH2, MLH1, and GTBP, by using a combination of different methods that included an in vitro synthesized protein assay, single-stran