DNA Microarrays: Gene Expression Applications

✍ Scribed by Bertrand R. Jordan (auth.), Dr. B. R. Jordan (eds.)

Publisher: Springer-Verlag Berlin Heidelberg
Year: 2001
Tongue: English
Leaves: 139
Series: Principles and Practice
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

This complete and practical manual on expression measurement using DNA arrays covers the existing methods (from nylon macroarrays to oligonucleotide chips) and includes detailed protocols. It has been written by practising scientists who have experienced the difficulties involved in actually using microarrays, and provides helpful advice and hints on setting up these powerful but sometimes tricky methods. Software, data mining procedures and probable future developments, which should be useful to any practising scientist interested in expression measurement, are also covered in this book. It also provides detailed protocols as well as many helpful hints to achieve experimental success and to avoid pitfalls.

✦ Table of Contents

Front Matter....Pages I-IX
DNA Arrays for Expression Measurement: An Historical Perspective....Pages 1-12
Expression Profiling with cDNA Microarrays: A User’s Perspective and Guide....Pages 13-33
cDNA Microarrays on Nylon Membranes with Enzyme Colorimetric Detection....Pages 35-54
cDNA Macroarrays and Microarrays on Nylon Membranes with Radioactive Detection....Pages 55-84
Oligonucleotide Chips for Expression Analysis: Principles and Practical Procedures....Pages 85-103
Gene Expression Data Mining and Analysis....Pages 105-129
Future Trends in the Use of DNA Arrays for Expression Measurement....Pages 131-138
Back Matter....Pages 139-140

✦ Subjects

Human Genetics; Cell Biology; Molecular Medicine

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