Redundant DNA methylation in colorectal
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Aster Alemayehu; Katarina Sebova; Ivana Fridrichova
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Article
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2008
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John Wiley and Sons
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English
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## Abstract Lynch syndrome is an inherited disease resulting predominantly in colorectal cancer (CRC). The crucial cause is DNA mismatch repair (MMR) malfunction that is associated mostly with __MLH1__ or __MSH2__ germline mutations. A significant hallmark of repair defects is a high level of insta