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DNA methylation in theAlcohol dehydrogenase-1gene of maize

โœ Scribed by Virginia Walbot; Christine Warren


Book ID
104614371
Publisher
Springer
Year
1990
Tongue
English
Weight
910 KB
Volume
15
Category
Article
ISSN
0167-4412

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โœฆ Synopsis


Using a battery of methylation-sensitive restriction enzymes, cytosine methylation at 23 sites in a 7.6 kb region surrounding the Alcohol dehydrogenase-1 (Adhl) gene was measured in DNA prepared from immature maize cobs. Both the 5' upstream region and the entire coding region were hypomethylated in the two alleles examined. Methylation in Adhl is independent of changes in Mutator transposable element methylation. The role of DNA methylation in Adhl gene regulation is discussed.


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