DNA methylation: Bisulphite modification and analysis
β Scribed by Clark, Susan J; Statham, Aaron; Stirzaker, Clare; Molloy, Peter L; Frommer, Marianne
- Book ID
- 109945942
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 557 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1750-2799
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## Abstract DNA methylation regulates gene expression primarily through modification of chromatin structure. Global methylation studies have revealed biologically relevant patterns of DNA methylation in the human genome affecting sequences such as gene promoters, gene bodies, and repetitive element