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DNA methylation based biomarkers: Practical considerations and applications

✍ Scribed by How Kit, Alexandre; Nielsen, Helene Myrtue; Tost, Jörg

Book ID
119195853
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
581 KB
Volume
94
Category
Article
ISSN
0300-9084

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## Abstract Gene silencing via promoter CpG island hypermethylation offers tumor cells growth advantages. This epigenetic event is pharmacologically reversible, and uncovering a unique set of methylation‐silenced genes in tumor cells can bring a new avenue to cancer treatment. However, high‐through