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DNA Methylation Assay for X-Chromosome Inactivation in Female Human iPS Cells

✍ Scribed by Lesli A. Kiedrowski; Gordana Raca; Jennifer J. Laffin; Benjamin S. Nisler; Kimberly Leonhard; Erik McIntire; Karen Dyer Mongomery


Book ID
107568218
Publisher
Humana Press Inc
Year
2011
Tongue
English
Weight
256 KB
Volume
7
Category
Article
ISSN
1550-8943

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Cloned human X chromosome-specific DNA segments, derived from a recombinant phage library enriched for the human X and previously localized to different regions of the X, were used as probes in Southern blots to confirm the nature of a deletion of the long arm of the X chromosome as del(X)(q13) in a