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DNA Methylation and Chromatin Structure Regulate T Cell Perforin Gene Expression

โœ Scribed by Lu, Q.; Wu, A.; Ray, D.; Deng, C.; Attwood, J.; Hanash, S.; Pipkin, M.; Lichtenheld, M.; Richardson, B.


Book ID
126855332
Publisher
American Association of Immunologists
Year
2003
Tongue
English
Weight
643 KB
Volume
170
Category
Article
ISSN
0022-1767

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Transcription factors control gene expression programs in the context of the chromatin structure of their target genes. DNA methylation, post-translational histone modifications such as acetylation and methylation, and higher order chromatin organization allow the maintenance of gene expression patt