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DNA Methylation and Cancer Development: Molecular Mechanism

✍ Scribed by Akhavan-Niaki, Haleh; Samadani, Ali Akbar

Book ID: 120250644
Publisher: Springer-Verlag
Year: 2013
Tongue: English
Weight: 691 KB
Volume: 67
Category: Article
ISSN: 1085-9195
DOI: 10.1007/s12013-013-9555-2

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The methylation of DNA is an epigenetic modification that can play an important role in the control of gene expression in mammalian cells. The enzyme involved in this process is DNA methyltransferase, which catalyzes the transfer of a methyl group from S-adenosyl-methionine to cytosine residues to f