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DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors

✍ Scribed by James F Amatruda, Julie A Ross, Brock Christensen, Nicholas J Fustino…

Book ID: 120680069
Publisher: BioMed Central
Year: 2013
Tongue: English
Weight: 579 KB
Volume: 13
Category: Article
ISSN: 1471-2407
DOI: 10.1186/1471-2407-13-313

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## Abstract Hypermethylation of tumor‐suppressor genes has been implicated in the pathogenesis of human cancers. Although a growing number of genes showing hypermethylation is being reported in human cancer, methylation profiles of tumor‐related genes in testicular neoplasms have not been well eluc