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DNA intercalative potential of marketed drugs testing positive in in vitro cytogenetics assays

โœ Scribed by Ronald D. Snyder; Douglas Ewing; Lawrence B. Hendry


Book ID
116759156
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
261 KB
Volume
609
Category
Article
ISSN
1383-5718

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P388 murine leukemic cells lines which were resistant (P388R) or sensitive (P388S) to adriamycin (adr) were used to evaluate the potential utility of in vitro clonogenic assays for detecting and quantitating the number of adr-resistant cells present in a cell mixture. The progeny of P388S cells that