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DNA hypermethylation of tumors from non-small cell lung cancer (NSCLC) patients is associated with gender and histologic type☆

✍ Scribed by Hawes, Stephen E.; Stern, Joshua E.; Feng, Qinghua; Wiens, Linda W.; Rasey, Janet S.; Lu, Hiep; Kiviat, Nancy B.; Vesselle, Hubert


Book ID
119320297
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
188 KB
Volume
69
Category
Article
ISSN
0169-5002

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## Abstract Our previous study showed a characteristic p53 mutational spectrum in lung tumors from lung cancer patients in the Western Pennsylvania region. To further understand the involvement of p53 mutations in lung tumor development, in this study we compared p53 mutational spectra and distribu