DNA haplotype-dependent differences in t
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S. Panserat; C. Mura; N. GΓ©rard; M. Vincent-Viry; M. M. Galteau; E. Jacqz-Aigrai
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Article
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1994
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Springer
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English
β 785 KB
The molecular basis for DNA haplotype-dependent debrisoquine 4-hydroxylase (CYP2D6) expression was explored by sequencing all of the nine exons of the CYP2D6 gene. Two distinct exon sequence frameworks of the CYP2D6 gene were found, each associated with specific BamHI-defined DNA haplotypes of the C