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DNA fragmentation and DNA repair synthesis induced in rat and human thyroid cells by chemicals carcinogenic to the rat thyroid

✍ Scribed by Francesca Mattioli; Antonietta Martelli; Marzia Gosmar; Claudia Garbero; Valeria Manfredi; Emanuela Varaldo; Gian Carlo Torre; Giovanni Brambilla

Book ID
116759180
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
161 KB
Volume
609
Category
Article
ISSN
1383-5718

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## Abstract Aflatoxin is a potent hepatocarcinogen. Biochemically the short‐term action which seems to be the most important is an inhibition of nucleic acid synthesis. Injection of low doses (from 500 to 1,000 ΞΌg/kg) made it possible to modulate the different inhibitions induced by aflatoxin. The