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DNA duplex membrane effect for the electrochemical detection of single-base DNA mutations

✍ Scribed by Luo, Chunxiong ;Mao, Yongdong ;Ouyang, Qi

Book ID
107382515
Publisher
Higher Education Press and Springer
Year
2006
Tongue
English
Weight
507 KB
Volume
1
Category
Article
ISSN
1673-3509

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## Background The high binding specificity of short 10 to 30 mer oligonucleotide probes enables single base mismatch (MM) discrimination and thus provides the basis for genotyping and resequencing microarray applications. Recent experiments indicate that the underlying principles governing DNA micr