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DNA double-strand breaks are not sufficient to initiate recruitment of TRF2

✍ Scribed by Williams, Eli S; Stap, Jan; Essers, Jeroen; Ponnaiya, Brian; Luijsterburg, Martijn S; Krawczyk, Przemek M; Ullrich, Robert L; Aten, Jacob A; Bailey, Susan M

Book ID
109916135
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
249 KB
Volume
39
Category
Article
ISSN
1061-4036

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Xrcc3 is recruited to DNA double strand
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## Abstract Rad51‐mediated homologous recombination (HR) is essential for maintenance of genome integrity. The Xrcc3 protein functions in HR DNA repair, and studies suggest it has multiple roles at different stages in this pathway. Defects in vertebrate __XRCC3__ result in elevated levels of sponta