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DNA double strand break repair in mammalian cells

✍ Scribed by Peter Karran


Book ID
117654652
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
170 KB
Volume
10
Category
Article
ISSN
0959-437X

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The end-joining pathway of DNA double-strand break (DSB) repair is necessary for proper V(D)J recombination and repair of DSB caused by ionizing radiation. This DNA repair pathway can either use short stretches of (micro)homology near the DNA ends or use no homology at all (direct end-joining). We d