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DNA demethylation modulates mouse leptin promoter activity during the differentiation of 3T3-L1 cells

โœ Scribed by N. Yokomori; M. Tawata; T. Onaya

Book ID
107656503
Publisher
Springer
Year
2002
Tongue
English
Weight
255 KB
Volume
45
Category
Article
ISSN
0012-186X

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A mouse cell line 3T3-L1 is differentiated into adipocytes when treated with an inducer cocktail (IDX) (insulin, dexametahsone, and a cAMP phosphodiesterase inhibitor of isobutyl-methylxanthine (IBMX)). Here, we report that PLD1, but not PLD2, mRNA and protein increased during the early differentiat