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DNA damage induction in human cells exposed to vanadium oxides in vitro

✍ Scribed by Juan J. Rodríguez-Mercado; Rodrigo A. Mateos-Nava; Mario A. Altamirano-Lozano

Book ID
116920506
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
316 KB
Volume
25
Category
Article
ISSN
0887-2333

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## Abstract The mechanism of Cr(VI) genotoxicity has still not been elucidated. We used Fpg‐modified comet assay to assess direct‐oxidative DNA damage on human lung (A549) and bronchial (BEAS‐2B) cells exposed to 0.1, 0.5, 1.0 and 10 μm sodium chromate for 0.5, 1 and 4 h. Moreover we evaluated apop