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DNA damage induced by doxorubicin, 4′-epidoxorubicin and their copper(II) complexes

✍ Scribed by Dario Cova; Marica Sassano; Elena Monti; Francesco Piccinini

Publisher: Springer-Verlag
Year: 1990
Tongue: English
Weight: 266 KB
Volume: 64
Category: Article
ISSN: 0340-5761
DOI: 10.1007/bf01971842

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## Abstract The reaction of 2,4,6‐tri(pyridyl)‐1,3,5‐triazine (ptz) and copper(II) salts in dmf/water (1:1) results in the hydrolysis of ptz and formation of the anions bis(2‐pyridylcarbonyl)amide (ptO~2~^–^) and bis(2‐pyridylamine)amide (ptN~2~^–^), which are found in the complexes [Cu(ptN~2~)(OAc