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DNA Cleavage by Copper Complexes of 2- and 3-Clip-Phen Derivatives

✍ Scribed by Marguerite Pitié; Christophe Boldron; Heinz Gornitzka; Catherine Hemmert; Bruno Donnadieu; Bernard Meunier

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
217 KB
Volume
2003
Category
Article
ISSN
1434-1948

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Efficient DNA Cleavage Induced by Copper
Efficient DNA Cleavage Induced by Copper(II) Complexes of Hydrolysis Derivatives of 2,4,6-Tri(2-pyridyl)-1,3,5-triazine in the Presence of Reducing Agents
✍ Joaquín Borrás; Gloria Alzuet; Marta González-Alvarez; Jose L. García-Giménez; B 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 269 KB 👁 1 views

## Abstract The reaction of 2,4,6‐tri(pyridyl)‐1,3,5‐triazine (ptz) and copper(II) salts in dmf/water (1:1) results in the hydrolysis of ptz and formation of the anions bis(2‐pyridylcarbonyl)amide (ptO~2~^–^) and bis(2‐pyridylamine)amide (ptN~2~^–^), which are found in the complexes [Cu(ptN~2~)(OAc