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DNA binding properties of the vitamin D3 receptor zinc finger region

✍ Scribed by Freedman, Leonard P.; Feldman, D.


Book ID
122011567
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
173 KB
Volume
17
Category
Article
ISSN
0169-6009

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The human vitamin D receptor (hVDR) possesses a unique array of five basic amino acids positioned between the two DNA-binding zinc fingers that is similar to well-characterized nuclear localization sequences in other proteins. When residues within this region are mutated to nonbasic amino acids, or