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DNA Binding, Photocleavage, and Topoisomerase Inhibition of Functionalized Ruthenium(II)-Polypyridine Complexes

✍ Scribed by Feng Gao; Hui Chao; Liang-Nian Ji


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
387 KB
Volume
5
Category
Article
ISSN
1612-1872

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✍ Jaroslav Malina; Michaelβ€…J. Hannon; Viktor Brabec πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 497 KB

## Abstract Metallosupramolecular chemistry was used to design a new class of synthetic agents, namely, tetracationic supramolecular cylinders, that bind strongly and noncovalently in the major groove of DNA. To gain additional information on interactions of the cylinders with DNA we explored DNA u