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DNA binding and nuclease activity of copper(II) complexes of tridentate ligands

✍ Scribed by Pankaj Kumar; Basudeb Baidya; Sumit Kumar Chaturvedi; Rizwan Hasan Khan; Debasis Manna; Biplab Mondal

Book ID
113642178
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
577 KB
Volume
376
Category
Article
ISSN
0020-1693

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## Abstract Two copper(II) terpyridine complexes, [Cu(atpy)(NO~3~)(H~2~O)](NO~3~) β‹… 3H~2~O (1) and [Cu(ttpy)(NO~3~)~2~] (2) (atpy = 4′‐__p__‐N9‐adeninylmethyl‐phenyl‐2,2β€²:6,2″‐terpyridine; ttpy = 4′‐__p__‐tolyl‐2,2β€²:6,2″‐terpyridine) exhibited high cytotoxicity, with average ten times more potency