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DNA Binding and Cleavage Studies of Two Palladium(II) Saccharinate Complexes with Terpyridine

✍ Scribed by Icsel, Ceyda; Yilmaz, Veysel T.

Book ID: 120017067
Publisher: Mary Ann Liebert
Year: 2013
Tongue: English
Weight: 368 KB
Volume: 32
Category: Article
ISSN: 1044-5498
DOI: 10.1089/dna.2012.1959

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## Abstract Two copper(II) terpyridine complexes, [Cu(atpy)(NO~3~)(H~2~O)](NO~3~) ⋅ 3H~2~O (1) and [Cu(ttpy)(NO~3~)~2~] (2) (atpy = 4′‐__p__‐N9‐adeninylmethyl‐phenyl‐2,2′:6,2″‐terpyridine; ttpy = 4′‐__p__‐tolyl‐2,2′:6,2″‐terpyridine) exhibited high cytotoxicity, with average ten times more potency