DNA Bending versus DNA End Joining Activity of HMGB1 Protein Is Modulated in Vitro by Acetylation †

Assembly of nuclear matrix–bound protein

Assembly of nuclear matrix–bound protein complexes involved in non-homologous end joining is induced by inhibition of DNA topoisomerase II

✍ Omar L. Kantidze; Olga V. Iarovaia; Sergey V. Razin 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 556 KB

## Abstract Topoisomerases maintain the DNA structure by relieving the torsional stress and alleviating other topological problems occurring in DNA during transcription and replication. Topoisomerase II appears to have a close association with the family of proteins involved in the organization of