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DNA Bending in Transcription Initiation

✍ Scribed by Kahn, J.D.; Crothers, D.M.


Book ID
111874949
Publisher
Cold Spring Harbor Laboratory Press
Year
1993
Tongue
English
Weight
45 KB
Volume
58
Category
Article
ISSN
0091-7451

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An increasing number of transcription factors both from prokaryotic and eukaryotic sources are found to bend the DNA upon binding to their recognition site. Bending can easily be detected by the anomalous electrophoretic behaviour of the DNA-protein complex or by increased cyclization of DNA fragmen