Antibodies to DNA
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Wayne F. Anderson; Miroslaw Cygler; Ralph P. Braun; Jeremy S. Lee
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Article
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1988
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John Wiley and Sons
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English
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The last application of the loop analysis work is to the design of novel proteins, using the techniques of protein engineering. Using this knowledge-based approach it should be possible to replace long loops by short loops and viceversa. Sequences of homologous proteins suggest that such mutations w