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DNA aneuploidy and histologic dysplasia in long-standing ulcerative colitis

✍ Scribed by R. Befrits; C. Hammarberg; C. Rubio; E. Jaramillo; B. Tribukait

Book ID
112679227
Publisher
Springer
Year
1994
Tongue
English
Weight
713 KB
Volume
37
Category
Article
ISSN
0012-3706

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Neoplastic progression in patients with chronic ulcerative colitis is characterized by the development of epithelial dysplasia, which is accompanied by genetic alterations. This study determined the time of onset of p53 and Ki-ras mutations as well as DNA aneuploidy during histological progression t