✦ LIBER ✦

DNA aneuploidy and high proliferative activity but not K-ras-2 mutations as independent predictors of clinical outcome in operable gastric carcinoma : Results of a 5-year Gruppo Oncologico dell'Italia Meridionale (GOIM) prospective study

✍ Scribed by Antonio Russo; Viviana Bazan; Manuela Migliavacca; Carla Tubiolo; Marcella Macaluso; Ines Zanna; Simona Corsale; Federica Latteri; Maria Rosaria Valerio; Gianni Pantuso; Vincenza Morello; Gabriella Dardanoni; Mario Adelfio Latteri; Giuseppe Colucci; Rosa Maria Tomasino; Nicola Gebbia

Publisher: John Wiley and Sons
Year: 2001
Tongue: English
Weight: 134 KB
Volume: 92
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(20010715)92:2<294::aid-cncr1322>3.0.co;2-9

No coin nor oath required. For personal study only.

✦ Synopsis

BACKGROUND.

The prognostic value of DNA ploidy, S-phase fraction (SPF) and K-ras-2 mutations in gastric carcinoma (GC) has not yet been clearly defined. The aim of this study was to clarify the association between biomolecular variables, tumor characteristics, and clinical outcome in GC patients.