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DNA amplification for detection of the XV-2c polymorphism linked to cystic fibrosis

✍ Scribed by Rosenbloom, Craig L.; Kerem, Bat-Sheva; Rommens, Johanna M.; Tsui, Lap-Chee; Wainwright, Brandon; Williamson, Robert; O'Brien, William E.; Beaudet, Arthur L.

Book ID
125527723
Publisher
Oxford University Press
Year
1989
Tongue
English
Weight
39 KB
Volume
17
Category
Article
ISSN
0305-1048

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DNA sequence analysis of the KM19 locus
DNA sequence analysis of the KM19 locus linked to cystic fibrosis
✍ R. Anwar; K. Murray; P. J. Hedge; J. C. Smith; A. F. Markham πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 531 KB

The PstI polymorphism detected by probe KM19 is a highly informative marker in linkage disequilibrium with the cystic fibrosis locus and has been used extensively for prenatal diagnosis. The currently available primers used for polymerase chain reaction- (PCR-) based analysis of this locus have been