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DNA adducts: effects of low exposure to ethylene oxide, vinyl chloride and butadiene

✍ Scribed by James A Swenberg; Amy Ham; Hasan Koc; Eric Morinello; Asoka Ranasinghe; Natalia Tretyakova; Patricia B Upton; Kuen-Yuh Wu


Book ID
117767916
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
211 KB
Volume
464
Category
Article
ISSN
1383-5718

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Human exposure to ethylene oxide and acrylonitrile may be monitored by determination of the products that these electrophilic compounds form with the amino terminal of hemoglobin. The procedure involves a modified Edman degradation, using the reagent pentafluorophenyl isothiocyanate, which cleaves t