DNA adduct formation in mice following dermal application of smoke condensates from cigarettes that burn or heat tobacco

Comparative study of DNA adduct formatio

Comparative study of DNA adduct formation in mice following inhalation of smoke from cigarettes that burn or primarily heat tobacco

✍ Buddy G. Brown; Chin K. Lee; Betsy R. Bombick; Paul H. Ayres; Arnold T. Mosberg; 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 168 KB 👁 3 views

The genotoxic potential of mainstream smoke from a test cigarette (TOB-HT) that primarily heats tobacco and a representative tobacco-burning cigarette (Kentucky reference 1R4F) was compared in male B6C3/F1 mice after nose-only inhalation exposure. Mice were exposed 1 hr per day, 5 days/ week for a 4