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DNA adduct formation in human hepatoma cells treated with 3-nitrobenzanthrone: analysis by the 32P-postlabeling method

✍ Scribed by Takaharu Kanno; Masanobu Kawanishi; Takeji Takamura-Enya; Volker M. Arlt; David H. Phillips; Takashi Yagi

Book ID
116759337
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
554 KB
Volume
634
Category
Article
ISSN
1383-5718

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Diesel exhaust is known to induce tumors in animals and is suspected of being carcinogenic in humans. Of the compounds found in diesel exhaust and in airborne particulate matter, 3-nitrobenzanthrone (3-NBA), is a particularly powerful mutagen. We investigated the capacity of 3-NBA to form DNA adduct