DMPK-associated myotonic dystrophy and CTG repeats in Alabama African Americans
β Scribed by RT Acton; CA Rivers; B Watson; SJ Oh
- Book ID
- 110888477
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 104 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0009-9163
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π SIMILAR VOLUMES
Length of (CTG)n triplet repeats in myotonic dystrophy protein kinase gene (DMPK) was estimated in tumors, normal tissues of the same organs, muscles, and leukocytes from three myotonic dystrophy (DM) patients and a non-DM patient. Using cDNA 25 as a probe, a Southern blot analysis of EcoRI- and Bgl
Myotonic dystrophy (MD), an autosomal dominant multisystemic disorder with a high phenotypic variability, is the most common muscular dystrophy in adult life. The mutation underlying DM has been characterized as an expanded CTG trinucleotide repeat sequence in the 3 ' untranslated region of a protei